Frequent low doses of intravenous mechlorethamine for late-stage mycosis fungoides lymphoma
نویسندگان
چکیده
منابع مشابه
Recent clinical evidence for topical mechlorethamine in mycosis fungoides
2014 Mycosis fungoides (MF) is a rare, potentially life-threatening cutaneous T-cell lymphoma characterized by cutaneous homing of neoplastic T lymphocytes. MF can mimic other diseases; clinicopathologic evaluation and imaging studies are essential. Biopsy of suspicious skin sites is essential for diagnosis. Topical mechlorethamine has been clinically tested over decades for the treatment of MF...
متن کاملMycosis fungoides: cutaneous T-cell lymphoma.
Most patients with mycosis fungoides are between 40 and 60 years of age. The disease has three clinical stages: (1) the premycotic, or patch, stage, consisting of macular, scaling, faint pink to red pruritic patches, usually on unexposed surfaces; (2) the mycotic, or plaque, stage, consisting of reddish, purple-brown plaques, often annular in shape and symmetric in distribution, and (3) the tum...
متن کاملOptimizing Care and Compliance for the Treatment of Mycosis Fungoides Cutaneous T-Cell Lymphoma With Mechlorethamine Gel.
BACKGROUND Mycosis fungoides is the most common form of cutaneous T-cell lymphoma (MF-CTCL). Quality nursing care is necessary for effective diagnosis and treatment of patients with MF-CTCL. Early-stage MF-CTCL (stages Ia and Ib) is most often managed in both dermatology and multidisciplinary settings. These stages can be effectively controlled by skin-directed therapies such as mechlorethamine...
متن کاملCutaneous T-Cell Lymphoma (Mycosis Fungoides).
IT IS IMPORTANT YOU DO NOT ACCEPT THE DIRE PROGNOSIS given in older medical literature you may find in a public library. Patients diagnosed and treated at early stages of CTCL can usually expect to live a NORMAL LIFESPAN and die of unrelated causes. For others, however, relapses are common, and treatment must either be lifelong in order to control the disease, or it must be repeated each time a...
متن کاملTreatment of early-stage mycosis fungoides with twice-weekly applications of mechlorethamine and topical corticosteroids: a prospective study.
OBJECTIVE To determine if a therapeutic regimen of twice-weekly applications of mechlorethamine hydrochloride and betamethasone dipropionate cream is effective in the treatment of early-stage mycosis fungoides while increasing cutaneous tolerance. DESIGN Prospective nonrandomized study conducted from November 1999 to November 2002. SETTING Eleven university or hospital dermatology departmen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1975
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197511)36:5<1613::aid-cncr2820360513>3.0.co;2-0